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| Item | Specification |
|---|---|
| Product Name | β-Amyloid (1-34) |
| CAS NO. | 186359-65-9 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₁₇₀H₂₅₃N₄₇O₅₂ |
| Molecular Weight | 3787.2 g/mol |
| Amino Acid Sequence | Not provided (per request) |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in 1M acetic acid, DMSO, or deionized water |
| Endotoxin | < 1 EU/mg |
| Biological Activity | Promotes neuronal apoptosis; involved in amyloid plaque formation; used for Alzheimer’s disease research |
| Storage Conditions | Store at -20°C, protected from light and moisture |
| Stock Location | USA / Germany / China (optional, based on actual stock) |
| MOQ | 1 mg |
β-Amyloid (1-34) exerts its biological effects by adopting conformations that facilitate oligomerization and fibrillization, leading to the formation of toxic aggregates that disrupt neuronal membrane integrity, induce oxidative stress, and trigger inflammatory responses. It also interferes with synaptic signaling and promotes apoptotic pathways in neuronal cells, mimicking the early events in Alzheimer’s pathology and serving as a reliable model for studying disease progression at the molecular level.
This peptide is primarily indicated for use in in vitro and in vivo research focused on neurodegenerative diseases, particularly Alzheimer’s disease. It is suitable for applications including amyloid aggregation studies, neurotoxicity assays, drug screening for anti-amyloid compounds, and development of diagnostic tools targeting early amyloid deposition. Researchers in academia, biotech, and pharmaceutical industries will find it indispensable for advancing understanding of neurodegeneration mechanisms.
While not intended for clinical use, β-Amyloid (1-34) has demonstrated high efficacy in preclinical models as a benchmark for evaluating the impact of potential therapeutics on amyloid-induced neurodegeneration. Its consistent aggregation properties and reproducible neurotoxic profile make it an essential reagent for validating drug candidates aimed at reducing amyloid burden, improving synaptic function, or delaying disease onset in experimental models.
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation. We can also customize packaging according to customer needs.
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
