| Item | Specification |
|---|---|
| Product Name | CTX IV (6-12) |
| CAS NO. | 115722-23-1 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₄₈H₇₀N₁₀O₇ |
| Molecular Weight | 899.14 g/mol |
| Amino Acid Sequence | Not provided (per request) |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in 1M acetic acid, DMSO, or deionized water |
| Endotoxin | < 1 EU/mg |
| Biological Activity | Specific cleavage site for cathepsin K; widely used as a standard for bone resorption biomarker quantification |
| Storage Conditions | Store at -20°C, protected from light and moisture |
| Stock Location | USA / Germany / China (optional, based on actual stock) |
| MOQ | 1 mg |
CTX IV (6-12) acts as a stable biomarker fragment generated during the enzymatic degradation of collagen by osteoclast-derived cathepsin K. Its presence in biological fluids such as urine or serum reflects active bone resorption rates, making it an essential tool for monitoring therapeutic interventions targeting bone loss and for understanding the pathophysiology of skeletal disorders.
This peptide is primarily indicated for use in academic and pharmaceutical research focused on bone metabolism, including studies on osteoporosis, Paget’s disease, primary hyperparathyroidism, and the efficacy of anti-resorptive therapies. It is suitable for laboratories conducting biomarker validation, assay development, and clinical trial sample analysis where precise measurement of bone breakdown markers is required.
As a gold-standard reference material, CTX IV (6-12) enables accurate, reproducible quantification of collagen degradation products across multiple platforms. Its consistent purity and defined structure ensure high inter-laboratory comparability, supporting robust clinical research outcomes. Researchers rely on this peptide to correlate bone resorption activity with disease progression, treatment response, and fracture risk assessment in both preclinical and clinical settings.
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
CTX IV (6-12) comes with a high purity of ≥98.0% determined by RP-HPLC. Every batch is manufactured under strict quality standards and is tested for low endotoxin levels (< 1 EU/mg) to ensure reproducible experimental and clinical results.
The lyophilized powder should be stored at -20°C, protected from light and moisture. Once reconstituted, avoid repeated freeze-thaw cycles by preparing appropriate single-use aliquots.
CTX IV (6-12) demonstrates good solubility in 1M acetic acid, DMSO, or sterile deionized water. Depending on your analytical assay or experimental requirements, select the compatible solvent.
Each shipment is accompanied by complete batch documentation including a Certificate of Analysis (COA), HPLC purity reports, and Mass Spectrometry (MS) analysis data. Third-party testing reports are also available upon request.
The MOQ is 1 mg. Products are shipped globally using express international air freight (DHL, FedEx, UPS, TNT) in specialized protective packaging designed to preserve stability during transit.