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| Item | Specification |
|---|---|
| Product Name | Sarafloxacin |
| CAS NO. | 98105-99-8 |
| Appearance | White to pale yellow crystalline powder |
| Molecular Formula | C₂₀H₁₇F₂N₃O₃ |
| Molecular Weight | 385.36 g/mol |
| Amino Acid Sequence | Not applicable |
| Purity (HPLC) | ≥98.0% |
| Solubility | Soluble in DMSO, methanol; slightly soluble in water; insoluble in non-polar solvents |
| Endotoxin | < 1 EU/mg |
| Biological Activity | Broad-spectrum fluoroquinolone antibacterial; inhibits bacterial DNA gyrase (Topoisomerase II) and Topoisomerase IV |
| Storage Conditions | Store at 2-8°C (short term) or -20°C (long term), protected from light and moisture |
| Stock Location | USA / Germany / China (optional, based on actual stock) |
| MOQ | 1 g / 5 g / 25 g |
Sarafloxacin exerts its bactericidal effect by selectively binding to and inhibiting two essential bacterial type II topoisomerases—DNA gyrase (Topoisomerase II) and Topoisomerase IV)—which prevents negative supercoiling of DNA and blocks DNA replication, transcription, and cell division, ultimately leading to double-strand DNA breaks and bacterial cell death.
This compound is indicated for veterinary pharmacological research, residue monitoring in food safety labs, and in vitro antimicrobial susceptibility studies targeting Escherichia coli, Salmonella spp., Pasteurella spp., and Staphylococcus aureus isolates from livestock and aquaculture. It is also used as an analytical reference in HPLC/MS methods for detecting fluoroquinolone residues in edible animal tissues.
Although not approved for human clinical use, sarafloxacin has demonstrated high efficacy in veterinary field trials for controlling respiratory and enteric infections in cattle, swine, and poultry, with low MIC₉₀ values against common food-animal pathogens. Its excellent tissue penetration and favorable pharmacokinetic profile in animals support its historical use, while current research focuses on resistance surveillance and withdrawal period determination for food safety compliance.
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation. We can also customize packaging according to customer needs.
Main Method: International Air Freight. We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Sarafloxacin (CAS NO. 98105-99-8) is a broad-spectrum fluoroquinolone antibacterial compound. It exerts bactericidal activity by selectively inhibiting bacterial DNA gyrase (Topoisomerase II) and Topoisomerase IV, disrupting negative supercoiling and hindering vital bacterial DNA replication and transcription.
Sarafloxacin is primarily utilized in veterinary pharmacological research, antimicrobial susceptibility tests (against pathogens such as E. coli, Salmonella spp., and S. aureus), food safety residue surveillance, and as an analytical reference standard for HPLC/MS testing in animal tissues.
Our Sarafloxacin is supplied with an HPLC purity of ≥98.0% and endotoxin levels under 1 EU/mg. Available standard MOQs include 1 g, 5 g, and 25 g, with flexible custom bulk quantities supported upon request.
To preserve stability and activity, Sarafloxacin should be stored at 2–8°C for short-term usage or maintained at -20°C for extended periods. It must be kept in a tightly sealed container protected from direct light, moisture, and extreme heat.
Every shipped batch is accompanied by comprehensive analytical records, including a Certificate of Analysis (COA), HPLC purity profiles, and mass spectrometry (MS) reports. Third-party lab validation reports are available upon request.
Shipments are handled via premier international air couriers such as DHL, FedEx, UPS, and TNT. Products are packed with specialized protective materials to ensure environmental stability and product integrity during transit.
