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| Item | Specification |
|---|---|
| Product Name | Bremelanotide (PT-141) |
| CAS NO. | 189691-06-3 / 1607799-13-2 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C50H68N14O10 |
| Molecular Weight | 1025.21 g/mol |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in water, dilute acetic acid; slightly soluble in DMSO |
| Endotoxin | ≤1 EU/mg |
| Biological Activity | Potent agonist at melanocortin-4 receptor (MC4R); stimulates sexual desire and arousal |
| Storage Conditions | Store at -20°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
Bremelanotide functions as a potent agonist primarily at melanocortin-4 receptors (MC4R) and to a lesser extent at MC3R located within the hypothalamus and limbic system. Upon subcutaneous administration, it crosses the blood-brain barrier to activate these receptors, triggering downstream signaling cascades that stimulate dopamine release and modulate neural circuits responsible for sexual motivation, thereby directly increasing sexual desire independently of the nitric oxide pathway utilized by traditional erectile dysfunction medications.
This product is specifically indicated for the treatment of acquired, generalized Hypoactive Sexual Desire Disorder (HSDD) in premenopausal women, addressing the distress associated with a persistent lack of sexual thoughts and receptivity. While its primary approved use is for female HSDD, it is also widely researched for its potential off-label application in treating male erectile dysfunction, particularly in cases where PDE5 inhibitors have failed, due to its central mechanism that can initiate arousal in the absence of external stimuli.
Clinical trials, including the pivotal RECONNECT studies, demonstrated that bremelanotide significantly increased the number of satisfying sexual events and reduced distress related to low sexual desire compared to placebo in women with HSDD. A meaningful clinical response was achieved by approximately 25% of treated patients, with effects typically onset within 45 minutes of administration and lasting for several hours, establishing its efficacy as an as-needed therapy for restoring sexual function and improving quality of life.
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation. We can also customize packaging according to customer needs.
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Bremelanotide acts as a potent agonist primarily targeting melanocortin-4 receptors (MC4R) and MC3R within the central nervous system. It triggers downstream signaling cascades that release dopamine and stimulate sexual desire directly through central pathways, distinct from the vascular mechanism of PDE5 inhibitors.
Our Bremelanotide is supplied with a purity grade of ≥98.0% verified by RP-HPLC, and endotoxin levels are strictly controlled at ≤1 EU/mg to maintain premium research and pharmaceutical standard quality.
According to clinical trial data, including the RECONNECT studies, clinical response is typically observed within approximately 45 minutes following subcutaneous administration, with efficacy sustaining for several hours.
The product should be stored at -20°C in a secure environment protected from direct light and moisture to maintain its stability, peptide integrity, and active biological activity.
Every batch comes with comprehensive analytical reports, including a Certificate of Analysis (COA), HPLC purity profile, mass spectrometry (MS) reports, and third-party laboratory verification upon request.
The minimum order quantity starts at 1g, with domestic stock readily available in the USA. Shipments are handled globally via prioritized air freight carriers including DHL, FedEx, UPS, and TNT with temperature-protective secure packaging.
